TY - JOUR PY - 1978// TI - Behavioral incapacitation of rats during full-scale combustion of natural-fiber and synthetic polymeric furnishings JO - Fire safety journal A1 - Mitchell, DS A1 - Rogers, WR A1 - Herrera, WR A1 - Switzer, WG SP - 187 EP - 197 VL - 1 IS - 3 N2 - Thirty Long-Evans rats served in each of six experiments to determine the time-course of behavioral incapacitation during exposure to full-scale combustion of household furnishings. Three experiments involved furniture constructed of natural-fiber materials, and three experiments involved furniture dominated by synthetic polymers. Groups of rats, previously trained to stable levels of performance on three tasks (rotorod, operant shock-avoidance, and a jump/escape test), were exposed to combustion products at three locations in a full-scale burn facility. Animals were removed from the exposure environment when they reached each of three operationally defined stages of behavioral incapacitation. Measures of time-to-incapacitation revealed that a given degree of behavioral dysfunction occurred 3 to 5 times sooner during exposure to the combustion of polymeric as compared to natural-fiber furnishings. Temperature, hydrocarbons, carbon dioxide, and oxides of nitrogen were the most frequent statistically significant correlates of time to behavioral incapacitation in polymeric fires; carbon monoxide, carbon dioxide, and total hydrocarbon concentration were the most frequent statistically significant correlates of behavioral dysfunction in natural-fiber fires. Animals that survived the first 24-hour interval after exposure showed no evidence of lasting behavioral incapacitation.
LA - SN - 0379-7112 UR - http://dx.doi.org/ ID - ref1 ER -