TY - JOUR PY - 2012// TI - Motor and somatosensory conversion disorder: a functional unawareness syndrome? JO - Journal of neuropsychiatry and clinical neurosciences A1 - Perez, David L. A1 - Barsky, Arthur J. A1 - Daffner, Kirk A1 - Silbersweig, David A. SP - 141 EP - 151 VL - 24 IS - 2 N2 - Although conversion disorder is closely connected to the origins of neurology and psychiatry, it remains poorly understood. In this article, the authors discuss neural and clinical parallels between lesional unawareness disorders and unilateral motor and somatosensory conversion disorder, emphasizing functional neuroimaging/disease correlates. Authors suggest that a functional-unawareness neurobiological framework, mediated by right hemisphere-lateralized, large-scale brain network dysfunction, may play a significant role in the neurobiology of conversion disorder. The perigenual anterior cingulate and the posterior parietal cortices are detailed as important in disease pathophysiology. Further investigations will refine the functional-unawareness concept, clarify the role of affective circuits, and delineate the process through which functional neurologic symptoms emerge.
Language: en
LA - en SN - 0895-0172 UR - http://dx.doi.org/10.1176/appi.neuropsych.11050110 ID - ref1 ER -