TY - JOUR PY - 2007// TI - Opioid overdose deaths can occur in patients with naltrexone implants JO - Medical journal of Australia A1 - Gibson, Amy E. A1 - Degenhardt, Louisa J. A1 - Hall, Wayne D. SP - 152 EP - 153 VL - 186 IS - 3 N2 - From Australian coronial records, we identified five deaths involving implantable naltrexone between 2000 and 2004. One man died from acute narcotism with a naltrexone implant in place and a blood naltrexone level of 0.3 mg/L. A woman died of combined drug effect (including naltrexone) accompanied by severe pain from a naltrexone implant site. These cases indicate that patients can die from opioid overdose with a naltrexone implant and blood naltrexone levels higher than reported blockade levels.
Language: en
LA - en SN - 0025-729X UR - http://dx.doi.org/ ID - ref1 ER -