TY  - JOUR
PY  - 2007//
TI  - The thrill can kill: murder by methylation
JO  - Molecular pharmacology
A1  - Barik, Sailen
SP  - 1203
EP  - 1205
VL  - 71
IS  - 5
N2  - Why babies of crack-cocaine mothers develop heart problems has always been a mystery. In this issue of Molecular Pharmacology, Zhang et al. (p. 1319) show that a specific methylation occurs at the protein kinase Cepsilon (PKCepsilon) promoter of the babies born of mother rats exposed to cocaine. This reduces the expression of PKCepsilon, a naturally cardioprotective enzyme, which provides a plausible molecular mechanism for cardiac failure.<p /> <p>Language: en</p>
LA  - en
SN  - 0026-895X
UR  - http://dx.doi.org/10.1124/mol.107.035196
ID  - ref1
ER  -