TY  - JOUR
PY  - 2012//
TI  - Wound-healing and benzodiazepines: does sleep play a role in this relationship?
JO  - Clinics (Sao Paulo)
A1  - Egydio, Flavia
A1  - Pires, Gabriel Natan
A1  - Tufik, Sergio
A1  - Andersen, Monica Levy
SP  - 827
EP  - 830
VL  - 67
IS  - 7
N2  - Patients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines on healing may not be direct but rather are modulated by alterations of the sleep architecture. This hypothesis is supported by studies that demonstrate the effects of benzodiazepines on the immune system and the inflammatory profile under both normal sleep conditions and during sleep deprivation, particularly rapid eye movement sleep deprivation.<p />  <p>Language: en</p>
LA  - en
SN  - 1807-5932
UR  - http://dx.doi.org/
ID  - ref1
ER  -