TY - JOUR PY - 2013// TI - The relationship between large cavum septum pellucidum and antisocial behavior, callous-unemotional traits and psychopathy in adolescents JO - Journal of child psychology and psychiatry A1 - White, Stuart F. A1 - Brislin, Sarah A1 - Sinclair, Stephen A1 - Fowler, Katherine A. A1 - Pope, Kayla A1 - Blair, R. James R. SP - 575 EP - 581 VL - 54 IS - 5 N2 - Background:  The presence of a large cavum septum pellucidum (CSP) has been previously associated with antisocial behavior/psychopathic traits in an adult community sample. Aims:  The current study investigated the relationship between a large CSP and symptom severity in disruptive behavior disorders (DBD; conduct disorder and oppositional defiant disorder). Method:  Structural MRI scans of youth with DBDs (N = 32) and healthy comparison youth (N = 27) were examined for the presence of a large CSP and if this was related to symptom severity. Results:  Replicating previous results, a large CSP was associated with DBD diagnosis, proactive aggression, and level of psychopathic traits in youth. However, the presence of a large CSP was unrelated to aggression or psychopathic traits within the DBD sample. Conclusions:  Early brain mal-development may increase the risk of a DBD diagnosis, but does not mark a particularly severe form of DBD within patients receiving these diagnoses.

Language: en

LA - en SN - 0021-9630 UR - http://dx.doi.org/10.1111/j.1469-7610.2012.02603.x ID - ref1 ER -