TY  - JOUR
PY  - 2012//
TI  - Sleep deprivation has a neuroprotective role in a traumatic brain injury of the rat
JO  - Neuroscience letters
A1  - Martinez-Vargas, Marina
A1  - Rojo, Francisco Estrada
A1  - Tabla-Ramon, Erika
A1  - Navarro-Argüelles, Hilda
A1  - Ortiz-Lailzon, Nathan
A1  - Hernández-Chávez, Alejandro
A1  - Solis, Barbara
A1  - Tapia, Ricardo Martínez
A1  - Arredondo, Adan Perez
A1  - Morales-Gomez, Julio
A1  - Gonzalez-Rivera, Ruben
A1  - Nava-Talavera, K.
A1  - Navarro, Luz
SP  - 118
EP  - 122
VL  - 529
IS  - 2
N2  - During the process of a brain injury, responses to produce damage and cell death are activated, but self-protective responses that attempt to maintain the integrity and functionality of the brain are also activated. We have previously reported that the recovery from a traumatic brain injury (TBI) is better in rats if it occurs during the dark phase of the diurnal cycle when rats are in the waking period. This suggests that wakefulness causes a neuroprotective role in this type of injury. Here we report that 24 h of total sleep deprivation after a TBI reduces the morphological damage and enhances the recovery of the rats, as seen on a neurobiological scale.<p />  <p>Language: en</p>
LA  - en
SN  - 0304-3940
UR  - http://dx.doi.org/10.1016/j.neulet.2012.09.037
ID  - ref1
ER  -