TY  - JOUR
PY  - 2013//
TI  - Clinical and neuropsychological aspects of non-fatal self-harm in schizophrenia
JO  - European psychiatry
A1  - Pluck, G.
A1  - Lekka, N. P.
A1  - Sarkar, S.
A1  - Lee, K. H.
A1  - Bath, P. A.
A1  - Sharif, O.
A1  - Woodruff, P. W. R.
SP  - 344
EP  - 348
VL  - 28
IS  - 6
N2  - PURPOSE: To investigate demographic, clinical and neuropsychological aspects of self-harm in schizophrenia and identify which are independently predictive of and therefore the most relevant to clinical intervention. SUBJECTS AND METHODS: Eighty-seven patients with schizophrenia were interviewed regarding substance misuse, depression, hopelessness, negative/positive symptoms and illness insight. Neuropsychological assessment included premorbid IQ, continuous performance test, cognitive-motor and trait impulsivity. A prospective three-month review of medical records was also undertaken. RESULTS: Fifty-nine patients (68%) reported past self-harm (including attempted suicide). Those with past self-harm, compared to those without, were significantly more likely to report depression, hopelessness, impulsivity, a family history of self-harm, polysubstance abuse and had higher premorbid IQ. Logistic regression revealed that depression, higher premorbid IQ and polysubstance abuse were independently linked to self-harm. Five participants attempted self-harm during the 3-month prospective follow-up period. These all had a history of past self-harm and were significantly more likely to have been depressed at the initial interview than those who did not go on to self-harm. DISCUSSION AND CONCLUSIONS: Independent predictors of self-harm in schizophrenia are premorbid IQ and polysubstance abuse. In addition, depression was both independently associated with past self-harm and predictive of self-harm in the follow-up period.<p />  <p>Language: en</p>
LA  - en
SN  - 0924-9338
UR  - http://dx.doi.org/10.1016/j.eurpsy.2012.08.003
ID  - ref1
ER  -