TY  - JOUR
PY  - 2013//
TI  - Acute poisoning with neonicotinoid insecticides: a case report and literature review
JO  - Basic and Clinical Pharmacology and Toxicology
A1  - Lin, Pei-Chen
A1  - Lin, Hung-Jung
A1  - Liao, Yu-Ying
A1  - Guo, How-Ran
A1  - Chen, Kuo-Tai
SP  - 282
EP  - 286
VL  - 112
IS  - 4
N2  - Neonicotinoids are a new class of insecticides widely applied for crop protection. These insecticides act as agonists at nicotinic acertylcholine receptors, which cause insect paralysis and death. The high specificity for receptors in insects was considered to possess highly selective toxicity to insects and relative sparing of mammals. However, an increasing number of cases of acute neonicotinoid poisoning have been reported in recent years. We reported a man who developed respiratory failure and shock after ingestion of neonicotinoid insecticide. A detailed literature review found that respiratory, cardiovascular and certain neurologic presentations are warning signs of severe neonicotinoid intoxication. The amounts of ingested neonicotinoid insecticide and the plasma neonicotinoid concentration are not useful guides for the management of intoxicated patients. Supportive treatment and decontamination are the practical methods for the management of all neonicotinoid poisoning patients.<p />  <p>Language: en</p>
LA  - en
SN  - 1742-7835
UR  - http://dx.doi.org/10.1111/bcpt.12027
ID  - ref1
ER  -