TY - JOUR PY - 2012// TI - Fatal poisoning by isoniazid and rifampicin JO - Indian journal of nephrology A1 - Sridhar, A. A1 - Sandeep, Y. A1 - Krishnakishore, C. A1 - Sriramnaveen, P. A1 - Manjusha, Y. A1 - Sivakumar, V. SP - 385 EP - 387 VL - 22 IS - 5 N2 - Isoniazid and rifampicin are used for management of tuberculosis. Acute poisoning due to isoniazid overdose is associated with repetitive generalized tonic-clonic seizures and severe metabolic acidosis. In toxic doses, rifampicin is known to produce hepatic, renal, hematological disorders, and convulsions. Sometimes, it may produce red man syndrome. We report a case of fatal poisoning with isoniazid and rifampicin. The case was characterized by late presentation, lactic acidosis, and renal failure.

Language: en

LA - en SN - 0971-4065 UR - http://dx.doi.org/10.4103/0971-4065.103930 ID - ref1 ER -