TY  - JOUR
PY  - 1991//
TI  - Neurofibrillary tangles in dementia pugilistica are ubiquitinated
JO  - Journal of neurology, neurosurgery, and psychiatry
A1  - Dale, G. E.
A1  - Leigh, P. N.
A1  - Luthert, P.
A1  - Anderton, B. H.
A1  - Roberts, G. W.
SP  - 116
EP  - 118
VL  - 54
IS  - 2
N2  - Ubiquitin, a protein thought to be involved in the ATP-dependent non-lysosomal degradation of abnormal proteins, has already been identified as a component of neurofibrillary tangles in Alzheimer's disease. We have examined ubiquitin immunoreactivity in a unique collection of brains from 16 ex-boxers including 11 with dementia pugilistica. Neurofibrillary tangles of dementia pugilistica were labelled with an affinity purified antiserum to ubiquitin, and BF10, a monoclonal antibody to a neurofilament epitope.<p /> <p>Language: en</p>
LA  - en
SN  - 0022-3050
UR  - http://dx.doi.org/
ID  - ref1
ER  -