TY  - JOUR
PY  - 2013//
TI  - Drug-induced liver injury associated with noni (Morinda citrifolia) juice and phenobarbital
JO  - Case reports in gastroenterology
A1  - Mrzljak, Anna
A1  - Kosuta, Iva
A1  - Skrtic, Anita
A1  - Kanizaj, Tajana Filipec
A1  - Vrhovac, Radovan
SP  - 19
EP  - 24
VL  - 7
IS  - 1
N2  - Noni juice is a popular herbal dietary supplement globally used for preventive or therapeutic purposes in a variety of ailments, claiming to exhibit hepatoprotective properties as well. Herein we present the case of a 38-year-old woman who developed acute liver injury associated with noni juice consumption on a long-term (9 months) anticonvulsant therapy. Clinical presentation and liver biopsy were consistent with severe, predominantly hepatocellular type of injury. Both agents were stopped and corticosteroids were initiated. Five months later the patient had fully recovered. Although in the literature the hepatotoxicity of noni juice remains speculative, sporadic but emerging cases of noni juice-associated liver injury address the need to clarify and investigate potential harmful effects associated with this supplement.<p />  <p>Language: en</p>
LA  - en
SN  - 1662-0631
UR  - http://dx.doi.org/10.1159/000343651
ID  - ref1
ER  -