TY - JOUR PY - 2013// TI - Prevalence of epileptic and nonepileptic events after pediatric traumatic brain injury JO - Epilepsy and behavior A1 - Matsumoto, Joyce H. A1 - Caplan, Rochelle A1 - McArthur, David L. A1 - Forgey, Marcy J. A1 - Yudovin, Sue A1 - Giza, Christopher C. SP - 233 EP - 237 VL - 27 IS - 1 N2 - Though posttraumatic epilepsy (PTE) is a prominent sequela of traumatic brain injury (TBI), other nonepileptic phenomena also warrant consideration. Within two UCLA pediatric TBI cohorts, we categorized five spell types: 1) PTE; 2) Epilepsy with other potential etiologies (cortical dysplasia, primary generalized); 3) Psychopathology; 4) Behavior misinterpreted as seizures; and 5) Other neurologic events. The two cohort subsets differed slightly in injury severity, but they were otherwise similar. Overall, PTE occurred in 40%, other epilepsy etiologies in 14%, and nonepileptic spells collectively in 46%. Among children with spells, PTE was associated with severe TBI (p=0.001), whereas psychopathology (p=0.014) and epilepsy with other etiologies (p=0.006) were associated with milder TBI severity. Posttraumatic epilepsy (p=0.002) and misinterpreted behavior (p=0.049) occurred with younger injury age. Psychopathology (p=0.020) and other neurologic events (p=0.002) occurred with older injury age. In evaluating possible PTE, clinicians should maintain a broad differential diagnosis to prevent misdiagnosis and inappropriate treatment.
Language: en
LA - en SN - 1525-5050 UR - http://dx.doi.org/10.1016/j.yebeh.2013.01.024 ID - ref1 ER -