TY  - JOUR
PY  - 2013//
TI  - Maintenance of wakefulness test scores and driving performance in sleep disorders patients and controls
JO  - International journal of psychophysiology
A1  - Philip, Pierre
A1  - Chaufton, Cyril
A1  - Taillard, Jacques
A1  - Sagaspe, Patricia
A1  - Leger, Damien
A1  - Raimondi, Monika
A1  - Vakulin, Andrew
A1  - Capelli, Aurore
SP  - 195
EP  - 202
VL  - 89
IS  - 2
N2  - OBJECTIVE: Sleepiness at the wheel is a risk factor for traffic accidents. Past studies have demonstrated the validity of the Maintenance of Wakefulness Test (MWT) scores as a predictor of driving impairment in untreated patients with obstructive sleep apnea syndrome (OSAS), but there is limited information on the validity of the maintenance of wakefulness test in predicting driving impairment in patients with hypersomnias of central origin (narcolepsy or idiopathic hypersomnia). The aim of this study was to compare the MWT scores with driving performance in sleep disorders patients and controls. METHODS: 19 patients suffering from hypersomnias of central origin (9 narcoleptics and 10 idiopatic hypersomnia), 17 OSAS patients and 14 healthy controls performed a MWT (4x40-minute trials) and a 40-minute driving session on a real car driving simulator. Participants were divided into 4 groups defined by their MWT sleep latency scores. The groups were pathological (sleep latency 0-19 minutes), intermediate (20-33 minutes), alert (34-40 minutes) and control (> 34 minutes). The main driving performance outcome was the number of inappropriate line crossings (ILC) during the 40 minute drive test. RESULTS: Patients with pathological MWT sleep latency scores (0-19 min) displayed statistically significantly more ILC than patients from the intermediate, alert and control groups (F (3, 46) = 7.47, p < 0.001). INTERPRETATION: Pathological sleep latencies on the MWT predicted driving impairment in patients suffering from hypersomnias of central origin as well as in OSAS patients. MWT is an objective measure of daytime sleepiness that appears to be useful in estimating the driving performance in sleepy patients.<p />  <p>Language: en</p>
LA  - en
SN  - 0167-8760
UR  - http://dx.doi.org/10.1016/j.ijpsycho.2013.05.013
ID  - ref1
ER  -