TY - JOUR PY - 1987// TI - Cross-tolerance between morphine and ethanol and their antinociceptive effects JO - Journal of studies on alcohol A1 - Malec, D. A1 - Kotlińska, J. A1 - Langwiński, R. SP - 507 EP - 510 VL - 48 IS - 5 N2 - Morphinization of mice (37.5 mg morphine) and rats (75 mg) with subcutaneously implanted pellets has resulted in tolerance to the antinociceptive effect of morphine, measured in the tail-immersion test. All animals also developed cross-tolerance to the analgesic effects of ethanol (2.8 g/kg intraperitoneally for mice, per os for rats). These results suggest a commonality between morphine and ethanol antinociceptive action.

Language: en

LA - en SN - 0096-882X UR - http://dx.doi.org/ ID - ref1 ER -