TY - JOUR PY - 1985// TI - Blood platelet uptake of serotonin in men alcoholics JO - Journal of studies on alcohol A1 - Kent, T. A. A1 - Campbell, J. L. A1 - Pazdernik, T. L. A1 - Hunter, R. A1 - Gunn, W. H. A1 - Goodwin, D. W. SP - 357 EP - 359 VL - 46 IS - 4 N2 - Blood platelet uptake of 3H-serotonin (5HT uptake) was determined in a group of inpatient alcoholics who had just undergone detoxication (N = 19) and an age-matched group of nonalcoholic controls (N = 19). Mean 5HT uptake was 18% lower in the alcoholics (p less than .01). A 3-min 5HT uptake of less than 6 pmoles/10(7) platelets identified 58% of the alcoholics, but only 15% of the controls had a 5HT uptake lower than this value. These results support the hypothesis that serotonergic dysfunction may exist in alcoholics.
Language: en
LA - en SN - 0096-882X UR - http://dx.doi.org/ ID - ref1 ER -