TY  - JOUR
PY  - 2010//
TI  - Acetaminophen: old drug, new warnings
JO  - Cleveland Clinic journal of medicine
A1  - Schilling, Amy
A1  - Corey, Rebecca
A1  - Leonard, Mandy
A1  - Eghtesad, Bijan
SP  - 19
EP  - 27
VL  - 77
IS  - 1
N2  - The US Food and Drug Administration (FDA), concerned about the incidence of acute liver failure due to acetaminophen (Tylenol) overdose, has mandated new labeling on acetaminophen packaging. It is also considering (but has not enacted) reducing the maximum daily dose from 4 g (possibly to 3,250 mg), banning acetaminophen-narcotic combination products, and changing the current maximum single dose of 1 g to prescription status, making 650 mg the highest recommended nonprescription dose. We review the epidemiology, toxicology, and management of acetaminophen overdose and steps the FDA and physicians can take to prevent it.<p /> <p>Language: en</p>
LA  - en
SN  - 0891-1150
UR  - http://dx.doi.org/10.3949/ccjm.77a.09084
ID  - ref1
ER  -