TY  - JOUR
PY  - 2013//
TI  - Blinded by the light: Retinal phototoxicity in the context of safety studies
JO  - Toxicologic pathology
A1  - Mudry, Maria Cristina De Vera
A1  - Kronenberg, Sven
A1  - Komatsu, Shun-ichiro
A1  - Aguirre, Gustavo D.
SP  - 813
EP  - 825
VL  - 41
IS  - 6
N2  - In this review, we discuss concepts and mechanisms of light damage and indicate how these might relate to preclinical safety studies. As well, we provide recommendations for evaluating the retina and developing protocols for evaluating a potential light damage mechanism in studies where retinal degeneration is observed.<p />  <p>Language: en</p>
LA  - en
SN  - 0192-6233
UR  - http://dx.doi.org/10.1177/0192623312469308
ID  - ref1
ER  -