TY  - JOUR
PY  - 2013//
TI  - An Assessment of In Ovo Toxicity of the Flame Retardant 1,2-Dibromo-4-(1,2-Dibromoethyl) Cyclohexane (TBECH) in the Zebra Finch
JO  - Bulletin of environmental contamination and toxicology
A1  - Currier, Heidi A.
A1  - Letcher, Robert J.
A1  - Williams, Tony D.
A1  - Elliott, John E.
SP  - 455
EP  - 459
VL  - 91
IS  - 4
N2  - Embryonic toxicity of a brominated flame retardant, TBECH (1,2-dibromo-4-(1, 2-dibromoethyl) cyclohexane) was investigated using the zebra finch (Taeniopygia guttata) as our model. Using in ovo dosing procedures, we injected the technical TBECH compound, consisting of 50:50 α-/β-isomers, directly into the yolk of freshly laid eggs at concentrations of 2.3-94 ng/g egg. No significant effects were observed in terms of growth or survival for either pre-hatch embryos or post-hatch chicks. Analysis of tissue samples at various developmental stages suggests that α-/β-TBECH was metabolized rapidly, and thus is unlikely to cause any direct, long-term effects on the development of zebra finch embryos or offspring.<p />  <p>Language: en</p>
LA  - en
SN  - 0007-4861
UR  - http://dx.doi.org/10.1007/s00128-013-1070-z
ID  - ref1
ER  -