TY  - JOUR
PY  - 2013//
TI  - Adaptations of motor neural structures' activity to lapses in attention
JO  - Cerebral cortex
A1  - Derosière, Gérard
A1  - Billot, Maxime
A1  - Ward, E. Tomas
A1  - Perrey, Stéphane
SP  - 66
EP  - 74
VL  - 25
IS  - 1
N2  - Sustained attention is fundamental for cognition and when impaired, impacts negatively on important contemporary living skills. Degradation in sustained attention is characterized by the time-on-task (TOT) effect, which manifests as a gradual increase in reaction time (RT). The TOT effect is accompanied by changes in relative brain activity patterns in attention-related areas, most noticeably in the prefrontal cortex (PFC) and the right parietal areas. However, activity changes in task-relevant motor structures have not been confirmed to date. This article describes an investigation of such motor-related activity changes as measured with 1) the time course of corticospinal excitability (CSE) through single-pulse transcranial magnetic stimulation; and 2) the changes in activity of premotor (PMC), primary motor (M1), PFC, and right parietal areas by means of near-infrared spectroscopy, during a sustained attention RT task exhibiting the TOT effect. Our results corroborate established findings such as a significant increase (P < 0.05) in lateral prefrontal and right parietal areas activity after the emergence of the TOT effect but also reveal adaptations in the form of motor activity changes-in particular, a significant increase in CSE (P < 0.01) and in primary motor area (M1) activity (P < 0.05).<p />  <p>Language: en</p>
LA  - en
SN  - 1047-3211
UR  - http://dx.doi.org/10.1093/cercor/bht206
ID  - ref1
ER  -