TY  - JOUR
PY  - 2013//
TI  - Health-related Quality of Life 12 months after severe traumatic brain injury: A prospective nationwide cohort study
JO  - Journal of rehabilitation medicine
A1  - Soberg, Helene L.
A1  - Roe, Cecilie
A1  - Anke, Audny
A1  - Arango-Lasprilla, Juan Carlos
A1  - Skandsen, Toril
A1  - Sveen, Unni
A1  - von Steinbuechel, Nicole
A1  - Andelic, Nada
SP  - 785
EP  - 791
VL  - 45
IS  - 8
N2  - OBJECTIVE: To assess health-related quality of life in individuals with severe traumatic brain injury at 12 months post-injury, applying the Quality of Life after Brain Injury (QOLIBRI) instrument, and to study the relationship between injury-related factors, post-injury functioning and health-related quality of life. Design/subjects: The study is part of a prospective, Norwegian multicentre study of adults (≥ 16 years old) with severe traumatic brain injury, as defined by a Glasgow Coma Scale score of 3-8 during the first 24 h post-injury. A total of 126 patients were included. METHODS: Socio-demographic data and injury severity variables were collected. Functioning at 3 and 12 months was assessed with the Glasgow Outcome Scale Extended (GOSE), the Functional Independence Measure (FIM), the Rivermead Post-concussion Questionnaire (RPQ), and the Hospital Anxiety and Depression Scale (HADS). Hierarchical regression analysis was applied. RESULTS: Mean QOLIBRI score was 68.5 (standard deviation = 18.8). Predictors of the QOLIBRI in the final regression model were: employment status (p = 0.05), GOSE (p = 0.05), RPQ (p < 0.001) and HADS (p < 0.001). The adjusted R2 showed that the model explained 64.0% of the variance in the QOLIBRI score. CONCLUSION: Symptom pressure and global functioning in the sub-acute phase of traumatic brain injury and psychological distress in the post-acute phase are important for health-related quality of life at 12 months post-injury. These domains should be the focus in rehabilitation aiming to improve health-related quality of life in patients with severe traumatic brain injury.<p />  <p>Language: en</p>
LA  - en
SN  - 1650-1977
UR  - http://dx.doi.org/10.2340/16501977-1158
ID  - ref1
ER  -