TY - JOUR PY - 2013// TI - Notes from the field: Acetyl fentanyl overdose fatalities - Rhode Island, March-May 2013 JO - MMWR: Morbidity and mortality weekly report SP - 703 EP - 704 VL - 62 IS - 34 N2 - In May 2013, the Rhode Island State Health Laboratories noticed an unusual pattern of toxicology results among 10 overdose deaths of suspected illicit drug users that had occurred during March 7-April 11, 2013. An enzyme-linked immunosorbent assay (ELISA) for fentanyl in blood was positive for fentanyl in all 10 cases, but confirmatory gas chromatography/mass spectrometry (GC/MS) did not detect fentanyl. The mass spectrum was instead consistent with acetyl fentanyl, a fentanyl analog. Acetyl fentanyl, a synthetic opioid, has not been documented in illicit drug use or overdose deaths, and is not available as a prescription drug anywhere. Animal studies suggest that acetyl fentanyl is up to five times more potent than heroin as an analgesic.
Language: en
LA - en SN - 0149-2195 UR - http://dx.doi.org/ ID - ref1 ER -