TY  - JOUR
PY  - 2013//
TI  - Depression and anxiety are associated with abnormal nocturnal blood pressure fall in hypertensive patients
JO  - Clinical and experimental hypertension
A1  - Sunbul, Murat
A1  - Sunbul, Esra Aydin
A1  - Kosker, Selcen Dogru
A1  - Durmus, Erdal
A1  - Kivrak, Tarik
A1  - Ileri, Cigdem
A1  - Oguz, Mustafa
A1  - Sari, Ibrahim
SP  - 354
EP  - 358
VL  - 36
IS  - 5
N2  - BACKGROUND: Previous studies have shown that depression and anxiety were independent risk factors for hypertension. Non-dipper hypertension is associated with higher cardiovascular mortality. The aim of this study was to evaluate the anxiety and depression scores in patients with dipper and non-dipper hypertension.     METHODS: The study sample consisted of 153 hypertensive patients. All patients underwent 24-h blood pressure monitoring. Patients were classified into two groups according to their dipper or non-dipper hypertension status. We evaluated results of the Hospital Anxiety and Depression Scale between groups.     RESULTS: Seventy-eight patients (38 male, mean age: 51.6 ± 12.5 years) had dipper hypertension while 75 patients (27 male, mean age: 55.4 ± 14.1 years) had non-dipper hypertension (p = 0.141, 0.072, respectively). Clinical characteristics were similar for both groups. Patients with non-dipper hypertension had significantly higher depression and anxiety scores compared to patients with dipper hypertension. Dipper and non-dipper status significantly correlated with anxiety (p: 0.025, r: 0.181) and depression score (p: 0.001, r: 0.255). In univariate analysis, smoking, alcohol usage, presence of diabetes, hyperlipidemia, anxiety score >8 and depression score >7 were predictors of dipper versus non-dipper status. In multivariate logistic regression analyses only depression score >7 was independent predictor of dipper versus non-dipper status (odds ratio: 2.74, confidence intervals: 1.41-5.37). A depression score of 7 or higher predicted non-dipper status with a sensitivity of 62.7% and specificity of 62.8%.     CONCLUSION: Non-dipper patients have significantly higher anxiety and depression scores compared to dipper patients. Evaluation of anxiety and depression in patients with hypertension might help to detect non-dipper group and hence guide for better management.<p />  <p>Language: en</p>
LA  - en
SN  - 1064-1963
UR  - http://dx.doi.org/10.3109/10641963.2013.827701
ID  - ref1
ER  -