TY  - JOUR
PY  - 2013//
TI  - Opioid poisonings and opioid adverse effects in workers in Washington State
JO  - American journal of industrial medicine
A1  - Fulton-Kehoe, Deborah
A1  - Garg, Renu K.
A1  - Turner, Judith A.
A1  - Bauer, Amy M.
A1  - Sullivan, Mark D.
A1  - Wickizer, Thomas M.
A1  - Franklin, Gary M.
SP  - 1452
EP  - 1462
VL  - 56
IS  - 12
N2  - OBJECTIVE: To examine trends in opioid poisonings and adverse effects in Washington (WA) State and nationally.     METHODS: We calculated rates of opioid poisonings and adverse effects and examined opioid prescriptions in the WA workers' compensation system, 2004-2010. Using Health Care Cost and Utilization Project (HCUP), Nationwide Inpatient Sample (NIS) data, we also calculated national rates of opioid poisonings and adverse effects, 1993-2010.     RESULTS: We identified 96 opioid poisonings and 312 opioid-related adverse effects in WA, 2004-2010. The rates did not change substantially over these years. Most poisonings and adverse effects occurred in cases without chronic opioid use and with prescribed doses <120 mg/day morphine-equivalent dose. Nationally, the rates of opioid poisonings and adverse effects increased significantly from 1993 to 2010.     CONCLUSIONS: Many poisonings and adverse effects occurred in patients without high dose or long-term opioid therapy, suggesting that opioid dosing and duration guidelines may not be sufficient to reduce morbidity related to prescription opioid use. Am. J. Ind. Med. © 2013 Wiley Periodicals, Inc.<p />  <p>Language: en</p>
LA  - en
SN  - 0271-3586
UR  - http://dx.doi.org/10.1002/ajim.22266
ID  - ref1
ER  -