TY - JOUR PY - 2014// TI - Using fMRI virtual-reality technology to predict driving ability after brain damage: a preliminary report JO - Neuroscience letters A1 - Vetivelu, Abeiramey A1 - Hung, Yuwen A1 - Tam, Fred A1 - Yan, Meishan A1 - Cusimano, Michael D. A1 - Graham, Simon J. A1 - Schweizer, Tom A. A1 - Hird, Megan SP - 41 EP - 46 VL - 558 IS - N2 - Until now there has been limited information regarding how the function of the human brain, the cerebellum, often affected by many neurological conditions and is important for movement control and planning, impacts driving ability. This study used the fMRI with virtual-driving technique to determine which aspects of daily driving performances are affected by cerebellar activation in healthy drivers (Experiment 1). It also investigated drivers with focal cerebellar lesions to identify how damage to this brain region impairs driving abilities. Results show that a healthy cerebellar function is responsible for basic driving performance related to motor-speed coordination; it is also responsible for executing complex driving behaviour related to temporal-motor integration. Drivers with cerebellar damage, as predicted, showed significantly compromised speed control during basic driving conditions, whereas their ability to perform in interactive driving situations was preserved. New insights into neural mechanisms and brain plasticity regarding driving behaviour are discussed. Strategies in assessing and rehabilitating drivers with related neurological conditions are provided.

Language: en

LA - en SN - 0304-3940 UR - http://dx.doi.org/10.1016/j.neulet.2013.10.065 ID - ref1 ER -