TY - JOUR PY - 1977// TI - Progestagen effects on elicitation of aggressive behaviour in male mice JO - Journal of endocrinology A1 - Soares, M. J. A1 - Kalberer, W. D. A1 - Erpino, M. J. SP - 507 EP - 510 VL - 73 IS - 3 N2 - The effects of progestagen on elicitation of aggressive behavior in male mice were tested. 48 mice were divided as follows: 1) 16 mice used as pheromone testers; 2) 24 mice bilaterally gonadectomized and subcutaneously implanted with either 20 mg testosterone (T), T + progesterone (P), or control beads; and 3) 8 mice sham-castrated and implanted with control beads. 4 days after the beginning of replacement therapy the treated mice were placed on an 18-hour food deprivation schedule in preparation for olfaction tests. A mouse was considered nonaggressive if response was absent (locating a food pellet) within 5 minutes. Zinc sulphate was administered intranasally to produce a peripheral olfactory dysfunction and produce anosmia. P failed to interfere with the actions of T in the production of aggression-eliciting pheromones and in the maintenance of the preputial and seminal vesicle-coagulating glands. Mice which were only castrated were attacked less than either T-treated or T + P-treated mice.

Language: en

LA - en SN - 0022-0795 UR - http://dx.doi.org/ ID - ref1 ER -