TY  - JOUR
PY  - 2013//
TI  - Use of fomepizole in pediatric methanol exposure: The first case report in Taiwan and a literature review
JO  - Pediatrics and neonatology
A1  - Chen, Tzu-Hua
A1  - Kuo, Chang-Hung
A1  - Huang, Chia-Tsuan
A1  - Wang, Wei-Li
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Methanol poisoning is rare in the pediatric population, but a delay in diagnosis and intervention may cause severe morbidity and mortality. The current therapy for methanol poisoning is ethanol or fomepizole, which acts as a competitive inhibitor of hepatic alcohol dehydrogenase to inhibit the production of toxic metabolites derived from the oxidation of methanol. However, clinical experience in pediatric methanol poisoning is limited, and the safety profiles of the antidotes have not been established in children, especially in Asian populations. This is the first case to describe the use of fomepizole in a child with methanol exposure in Taiwan.<p />  <p>Language: en</p>
LA  - en
SN  - 1875-9572
UR  - http://dx.doi.org/10.1016/j.pedneo.2013.08.009
ID  - ref1
ER  -