TY - JOUR PY - 1995// TI - Cimetidine and the blood alcohol curve: A case study and review JO - Journal (Canadian Society of Forensic Science) A1 - Westenbrink, W. SP - 165 EP - 170 VL - 28 IS - 2 N2 - Controversy as to whether or not Cimetidine and other H2-receptor antagonists are capable of raising an individual's Blood Alcohol Concentration (BAC) has surfaced in the scientific literature in the recent past. This effect of Cimetidine has been attributed to the inhibition of Alcohol Dehydrogenase (ADH) in the stomach, the site where some authors believe significant "first pass metabolism" of ethyl alcohol takes place. The possibility of increasing an individual's BAC has forensic implications particularly in impaired driving cases. A review of one such case is described together with a brief scientific overview of the effects of Cimetidine on the blood alcohol curve.

LA - en SN - 0008-5030 UR - http://dx.doi.org/10.1080/00085030.1995.10757480 ID - ref1 ER -