TY  - JOUR
PY  - 2003//
TI  - Neuropsychological effects of long-term opioid use in chronic pain patients
JO  - Journal of pain and symptom management
A1  - Jamison, Robert N.
A1  - Schein, Jeff R.
A1  - Vallow, Susan
A1  - Ascher, Steven
A1  - Vorsanger, Gary J.
A1  - Katz, Nathaniel P.
SP  - 913
EP  - 921
VL  - 26
IS  - 4
N2  - Opioids are thought to worsen the performance of psychomotor tasks due to their sedating and mental-clouding effects. As a result, some safety regulations currently restrict the use of opioids when driving or using heavy equipment. We investigated the psychomotor effects of long-term opioid use in 144 patients with low back pain. All subjects were administered two neuropsychological tests (Digit Symbol and Trail Making Test-B) before being prescribed opioids for pain; tests were re-administered at 90- and 180-day intervals. Test scores significantly improved while subjects were taking opioids for pain, which suggests that long-term use of oxycodone with acetaminophen or transdermal fentanyl does not significantly impair cognitive ability or psychomotor function.<p /> <p>Language: en</p>
LA  - en
SN  - 0885-3924
UR  - http://dx.doi.org/
ID  - ref1
ER  -