TY  - JOUR
PY  - 1978//
TI  - The effect of nitrazepam on manual skill, grip strength, and reaction time with special reference to subjective evaluation of effects on sleep
JO  - Acta Pharmacologica et Toxicologica (Copenh).
A1  - Lahtinen, A.
A1  - Lahtinen, U.
A1  - Pekkola, P.
SP  - 130
EP  - 134
VL  - 42
IS  - 2
N2  - The effects of 5 and 10 mg oral nitrazepam doses on manual skills, grip strength, and reaction time 8 hours after ingestion of the drugs were studied in 34 healthy female volunteers aged 19-22 years. 5 mg nitrazepam caused a slight but insignificant decrease in psychomotor skills. With 10 mg psychomotor skills were influenced significantly. Grip strength and reaction time were not influenced either by the 5 or 10 mg doses. The investigators corroborate the value of the established effects of nitrazepam as a hypnotic, but recommend that caution should be excercised in prescribing the drug as a hypnotic (especially in doses exceeding 5 mg) to work-aged subjects as there is a risk of significant effect on the psychomotor skills. Furthermore, the drug may cause fatigue.<p /> <p>Language: en</p>
LA  - en
SN  - 0001-6683
UR  - http://dx.doi.org/
ID  - ref1
ER  -