TY - JOUR PY - 1978// TI - Single case study. Possible organophosphate-induced parkinsonism JO - Journal of nervous and mental disease A1 - Davis, K. L. A1 - Yesavage, J. A. A1 - Berger, P. A. SP - 222 EP - 225 VL - 166 IS - 3 N2 - A case of possible organophosphate-induced parkinsonism is presented. The patient was a crop duster with numerous episodes of acute organophosphate intoxication and chronic organophosphate exposure. The etiology of parkinsonism is discussed in terms of a balance hypothesis between cholinergic and dopaminergic neurotransmission in the striatum. A possible relationship between chronic organophosphate exposure and alterations in central cholinergic or dopaminergic activity is suggested. The course of this patient raises the possibility that agricultural workers may be at risk for the late development of parkinsonism.
Language: en
LA - en SN - 0022-3018 UR - http://dx.doi.org/ ID - ref1 ER -