TY  - JOUR
PY  - 2014//
TI  - An examination of 1-year adherence and persistence rates to antiepileptic medication in children with newly diagnosed epilepsy
JO  - Journal of pediatric psychology
A1  - Aylward, Brandon S.
A1  - Rausch, Joseph R.
A1  - Modi, Avani C.
SP  - 66
EP  - 74
VL  - 40
IS  - 1
N2  - OBJECTIVE: The primary aim of the current study was to use new methods to examine 1-year quality of medication dosing (adherence) and continuation with medication treatment (persistence) rates to antiepileptic drugs (AEDs) in children with newly diagnosed epilepsy. <br><br>METHODS: Medication-taking behaviors of AEDs were assessed using electronic monitors for 117 children with newly diagnosed epilepsy for the first year after diagnosis. <br><br>RESULTS: Approximately 15% of participants were categorized as nonpersistent (i.e., failed to take medication for >15 consecutive days) 6-months after AED initiation, which increased to 26.6% of participants at 1 year. The majority of medication dosing events took place within a +/-2-hr interval as recommended. The group with lower socioeconomic status demonstrated more nonpersistence over time. <br><br>CONCLUSION: Examining adherence and persistence in medication taking behaviors may yield different types of data for clinical and research purposes.<p />  <p>Language: en</p>
LA  - en
SN  - 0146-8693
UR  - http://dx.doi.org/10.1093/jpepsy/jsu010
ID  - ref1
ER  -