TY  - JOUR
PY  - 1978//
TI  - The interaction between ethanol and antihistamines. 1: Dexchlorpheniramine
JO  - Medical journal of Australia
A1  - Franks, H. M.
A1  - Hensley, V. R.
A1  - Hensley, W. J.
A1  - Starmer, G. A.
A1  - Teo, R. K.
SP  - 449
EP  - 452
VL  - 1
IS  - 8
N2  - Thirteen paid student volunteers (9 male, 4 female) were used in a double-blind crossover experiment to investigate the effects of a therapeutic dose of dexchlorpheniramine alone, and in combination with a social dose of ethanol on perceptual, cognitive and motor functions. Both ethanol (0.75 g/kg) and dexchlorpheniramine (4 mg/70 kg) were given orally. Although a synergistic effect of dexchlorpheniramine with ethanol was only observed in some of the tests, a delayed recovery from the effects of the combination was noted. Subjective data indicated that the sedative effects of dexchlorpheniramine were more pronounced in the presence of ethanol.<p /> <p>Language: en</p>
LA  - en
SN  - 0025-729X
UR  - http://dx.doi.org/
ID  - ref1
ER  -