TY  - JOUR
PY  - 1981//
TI  - Acetominophen toxicity. Report of two cases
JO  - Oral surgery, oral medicine, and oral pathology
A1  - Golden, D. P.
A1  - Mosby, E. L.
A1  - Smith, Deborah J.
A1  - Mackercher, P.
SP  - 385
EP  - 389
VL  - 51
IS  - 4
N2  - Both chronic low-dose use within accepted therapeutic limits and acute overdosage of acetominophen with as little as 7 Gm or 150 mg./kg. can result in irreversible centrilobular hepatic necrosis. Prompt and proper treatment with N-acetyl-cysteine in strict adherence to accepted protocol will prevent potentially fatal results. Clinicians who prescribe acetominophen must likewise be cognizant of other potential side effects, such as methemoglobinemia, hemolysis, and prothrombin suppression.<p /> <p>Language: en</p>
LA  - en
SN  - 0030-4220
UR  - http://dx.doi.org/
ID  - ref1
ER  -