TY  - JOUR
PY  - 2014//
TI  - Risk and predictors of attempted and completed suicide in patients with hematological malignancies
JO  - Psycho-oncology
A1  - Mohammadi, Mohammad
A1  - Moradi, Tahereh
A1  - Bottai, Matteo
A1  - Reutfors, Johan
A1  - Cao, Yang
A1  - Smedby, Karin E.
SP  - 1276
EP  - 1282
VL  - 23
IS  - 11
N2  - BACKGROUND: Hematological malignancies can cause high levels of distress, but few studies have assessed risk of suicidal behavior among these patients. <br><br>METHODS: We evaluated risk of attempted and completed suicide in a cohort of 46,309 patients diagnosed with malignant lymphoma, myeloma and leukemia in Sweden 1992 to 2009 and 107,736 cancer-free subjects, using Poisson regression. <br><br>RESULTS: In all, 146 suicide attempts and 63 completed suicides occurred during a median follow up of 3.1 years (maximum 19 years). The risk of completed suicide was 3.5-fold increased among patients with myeloma [incidence rate ratio (IRR) = 3.52, 95% confidence interval (CI) = 2.05-6.03] and 1.9-fold increased among patients with lymphoma (IRR = 1.87, 95% CI = 1.31-2.67) but not significantly increased among patients with leukemia. Risk of attempted suicide was increased among patients with myeloma (IRR = 2.13, CI = 1.39-3.26) and lymphoma (IRR = 1.34, 95% CI = 1.07-1.69). Both male and female patients were at increased risk of attempted as well as completed suicide. A pre-malignant history of mental disorders conferred 15-fold to 30-fold increased risks, but elevated risks were also observed among patients without such history. <br><br>CONCLUSIONS: Suicidal actions in patients with hematological malignancies have high suicidal intent, and that subgroups of patients should be monitored for suicidal ideation. Copyright © 2014 John Wiley & Sons, Ltd.<p />  <p>Language: en</p>
LA  - en
SN  - 1057-9249
UR  - http://dx.doi.org/10.1002/pon.3561
ID  - ref1
ER  -