TY  - JOUR
PY  - 2014//
TI  - Cognitive inhibition in older high-lethality suicide attempters
JO  - International journal of geriatric psychiatry
A1  - Richard-Devantoy, Stéphane
A1  - Szanto, Katalin
A1  - Butters, Meryl A.
A1  - Kalkus, Jan
A1  - Dombrovski, Alexandre Y.
SP  - 274
EP  - 283
VL  - 30
IS  - 3
N2  - BACKGROUND: People who attempt suicide often display cognitive impairments, particularly poor cognitive control. Could poor cognitive control contribute to high suicide rates in old age? A component of cognitive control, cognitive inhibition-active suppression of task-irrelevant processing-is very sensitive to aging and has been linked to attempted suicide. We investigated cognitive inhibition in older high-lethality suicide attempters, closely resembling suicide victims, as well as low-lethality attempters, and control groups with and without depression and suicidal ideation. <br><br>METHODS: A total of 102 participants aged 60 years and older (17 psychiatrically healthy control subjects, 38 depressed control subjects, 16 suicide ideators, 14 low-lethality suicide attempters, and 17 high-lethality suicide attempters) underwent comprehensive clinical and cognitive assessments. They completed the Delis-Kaplan Executive Function System Color-Word Interference Test, a validated modification of the Stroop test. <br><br>RESULTS: High-lethality suicide attempters demonstrated a distinct pattern of cognitive inhibition deficits. Compared with psychiatrically healthy control subjects and suicide ideators, high-lethality attempters took longer to complete inhibition trials, even after accounting for potential confounding factors (age, education, Mini mental state examination score, information processing speed, and accuracy). Compared with non-suicidal depressed and healthy control subjects, low-lethality suicide attempters committed more uncorrected errors; however, this difference was not specific to the inhibition condition. <br><br>CONCLUSIONS: Older suicide attempters are a cognitively heterogeneous group. Poor cognitive control in high-lethality attempters may undermine their ability to solve real-life problems, precipitating a catastrophic accumulation of stressors. Meanwhile, low-lethality attempters' poor performance may reflect a careless approach to the task or faulty monitoring. Copyright © 2014 John Wiley & Sons, Ltd.<p />  <p>Language: en</p>
LA  - en
SN  - 0885-6230
UR  - http://dx.doi.org/10.1002/gps.4138
ID  - ref1
ER  -