TY - JOUR PY - 1979// TI - Effects of exercise in the heat on predisposition to heatstroke JO - Medicine and science in sports A1 - Hubbard, R. W. SP - 66 EP - 71 VL - 11 IS - 1 N2 - This article reviews briefly the historical origins for both the cardiovascular and neural-anhidrotic concepts of heatstroke pathophysiology. It describes how deemphasis of the role of anhidrosis as the primary cause of heatstroke has resulted in: (a) an increased acceptance of animal models for heatstroke research; (b) further evidence that rigid reliance on the classic heatstroke symptoms (coma, anhidrosis, and a fever over 106 degrees F) can result in underdiagnosis; and (c) new research consistant with the hypothesis that exhaustive physical effort, by worsening circulatory collapse and metabolic acidosis predisposes tissue to hyperthermic injury and, as a result, substantially lowers the threshold for heatstroke injury and mortality. Thus, a new hypothesis combining the essential features of both direct thermal injury and cardiovascular origins of heatstroke pathophysiology may be necessary.
Language: en
LA - en SN - 0025-7990 UR - http://dx.doi.org/ ID - ref1 ER -