TY  - JOUR
PY  - 1985//
TI  - Behavioral pharmacokinetics of marijuana
JO  - Psychopharmacology
A1  - Barnett, G.
A1  - Licko, V.
A1  - Thompson, T.
SP  - 51
EP  - 56
VL  - 85
IS  - 1
N2  - Male volunteer subjects smoked one marijuana cigarette containing 100, 200, or 250 micrograms/kg delta-9-tetrahydrocannabinol (THC) and were tested on three perceptual-motor performance measures related to driving. Performance was measured and blood samples were collected for 24 h after smoking. The covariation between pharmacodynamics of performance and pharmacokinetics of THC in plasma was investigated for decrement in performance as the response to smoking a single marijuana cigarette. A significant linear correlation was found between tracking errors under divided attention and THC plasma levels over 5-25 ng/ml for approximately 2 h after smoking. A sigmoid relation was found between critical tracking breakpoint and log THC plasma levels over 2-25 ng/ml for approximately 7 h after smoking.    Keywords: Cannabis impaired driving <p />  <p>Language: en</p>
LA  - en
SN  - 0033-3158
UR  - http://dx.doi.org/
ID  - ref1
ER  -