TY - JOUR PY - 1978// TI - Post-mortem alcohol concentrations iii. the concentration of alcohol in the cerebro-spinal fluid and vitreous humor JO - Blutalkohol A1 - Gelbke, H. P. A1 - Lesch, P A1 - Schmidt, G. SP - 115 EP - 124 VL - 15 IS - 2 N2 - Simultaneous determinations of alcohol concentrations in blood (BAC), vitreous humor (VAC) and cerebro-spinal fluid (CAC) were carried out on samples from 440 bodies having alcohol in these body fluids. The least square regression analysis for VAC and CAC gave a coefficient of correlation, r=0.954, and the equation for the regression line: VAC=0.90 x CAC - 0.04. From this a conversion factor F(C-V) of 0.90 is derived for the calculation of the VAC from CAC. This value lies clearly below the theoretical expected value of F(C-V)=0.99. It may hence be inferred that diffusion equilibrium of alcohol between blood and cerebro-spinal fluid occurs rapidly and in comparison more slowly between blood and vitreous humor. Similar results were obtained with the analysis of cases in which the VAC and/or the CAC was lower than the BAC.

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