TY - JOUR PY - 2014// TI - Oxidative stress and antioxidant therapy with the inclusion alpha-lipoic acid in acute poisoning by herbicide based on 2,4-dichlorphenoxyacetic acid JO - Likars'ka Sprava / Ministerstvo Okhorony Zdorov'ia Ukraïny SP - 140 EP - 145 VL - IS - 1-2 N2 - In patients with acute poisoning amine salt herbicide 2,4-D develops oxidative stress with simultaneous inhibition of intracellular and extracellular antioxidant factors. These changes are more pronounced with neurological disorders that occur in conjunction with a toxic damage of liver or heart. The inclusion of a comprehensive detoxification therapy alpha-lipoic acid not only promotes a more pronounced therapeutic effect but also an earlier recourse cytolytic syndrome, a marked recovery of levels of malondialdehyde and indices of antioxidant system (superoxide dismutase and ceruloplasmin) than for patients in the comparison group.

Language: uk

LA - uk SN - 1019-5297 UR - http://dx.doi.org/ ID - ref1 ER -