TY - JOUR PY - 1978// TI - Influence of heat, wind, and humidity on ultraviolet radiation injury JO - National Cancer Institute monograph A1 - Owens, D. W. A1 - Knox, J. M. SP - 161 EP - 167 VL - IS - 50 N2 - We investigated the influence of heat, wind, and humidity on UVR-induced acute and chronic skin damage of experimental animals housed in environmental chambers and irradiated under controlled conditions. Hairless mice (strain HRS/J) irradiated after an increase of 10 degrees F in skin temperature had more skin damage than irradiated controls. Significantly more Swiss albino mice irradiated for 400 days while maintained at 90 degrees F developed tumors than did those receiving the same amount of UVR but maintained at room temperature. Mice exposed to UVR daily for 4 weeks while kept in wind of 7 mph had greater damage and slower recovery than animals irradiated but protected from wind. Wind also accelerated tumorigenesis in mice than received chronic UVR. Mice kept at 80% relative humidity and given a single dose of UVR had greater skin injury than animals irradiated while at 5% relative humidity. High midity also appears to accelerate skin cancer formation in animals that were exposed to chronic UVR.

Language: en

LA - en SN - 0083-1921 UR - http://dx.doi.org/ ID - ref1 ER -