TY  - JOUR
PY  - 1977//
TI  - Biphasic time-course of alcohol-induced changes in electrodermal activation parameters
JO  - Blutalkohol
A1  - Richter, R.
A1  - Kielholz, P.
A1  - Hobi, V.
SP  - 279
EP  - 291
VL  - 14
IS  - 5
N2  - Alcohol-induced changes in activation have been investigated following the time-course of blood-alcohol concentrations. A single dose of 0.77 g/kg alcohol (vodka) was administered to 16 healthy men (mean age 36.9 years) serving as their own controls in a change-over design. To measure the CNS-activation level, two variables of electrodermal activity - the spontaneous fluctuation frequency and the skin resistance response - were used as indicators of habituation of the orienting response to an acoustic stimulus. In both variables the authors found a biphasic time-course of the alcohol effect upon the activation level, i.e. increased activation up to 60 min (the absorption phase), and well-known decreased activation in the post-absorption phase. It has been supposed that this biphasic effect is due to two relatively separable processes, which constitute by their phase-shifted antagonism the demonstrated effect, i.e. increased nonspecific tonic activation in the absorption phase and decreased specific phasic activation in the post-absorption phase.<p />
LA  - de
SN  - 0006-5250
UR  - http://dx.doi.org/
ID  - ref1
ER  -