TY  - JOUR
PY  - 1979//
TI  - Psychotropic drugs as behavioral teratogens
JO  - Science
A1  - Vorhees, C. V.
A1  - Brunner, R. L.
A1  - Butcher, R. E.
SP  - 1220
EP  - 1225
VL  - 205
IS  - 4412
N2  - Three psychotropic drugs were administered to pregnant rats and were then evaluated for their behavioral and reproductive effects in the offspring. Control rats received either saline or vitamin A. Prochlorperazine had the most disruptive effects on reproduction and growth, but had the least effect on behavior. Propoxyphene had no apparent effects on reproduction or growth, but produced a variety of behavioral changes. Fenfluramine was intermediate in its effects on reproduction and growth and had behavioral effects that were revealed in tests of preweaning development. The data suggest that systematic tests of behavior add important information to evaluations of reproductive toxicity that cannot, at present, be obtained by other means.<p /> <p>Language: en</p>
LA  - en
SN  - 0036-8075
UR  - http://dx.doi.org/
ID  - ref1
ER  -