TY - JOUR PY - 1979// TI - Aggression in humans correlates with cerebrospinal fluid amine metabolites JO - Psychiatry research A1 - Brown, G. L. A1 - Goodwin, F. K. A1 - Ballenger, J. C. A1 - Goyer, P. F. A1 - Major, L. F. SP - 131 EP - 139 VL - 1 IS - 2 N2 - Cerebrospinal fluid of the major central metabolites of serotonin (5HT), norepinephrine (NE), and dopamine (DA)--5-hydroxyindoleacetic acid (5HIAA), 3-methoxy-4-hydroxy=phenylglycol (MHPG), and homovanillic acid (HVA), respectively--were studied in a group of 26 age-similar military men with no history of major psychiatric illness, but with various personality disorders and difficulties adjusting to military life. Independently scored history of aggressive behavior showed a significant negative correlation with 5HIAA (r = -0.78) and a significant positive correlation with MHPG (r = 0.64).

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