TY  - JOUR
PY  - 1999//
TI  - Nutritive influences on endogenous methanol concentrations and endogenous methanol formation
JO  - Blutalkohol
A1  - Stranger, J
A1  - Graw, M.
A1  - Besserer, K.
A1  - Haffner, H. T.
SP  - 269
EP  - 275
VL  - 36
IS  - 5
N2  - Endogenous methanol levels and production were assessed in four test persons on three occasions: first, after no food had been consumed and after medicinal bowel cleansing, second, after a 2-day period of eating more or less low-pectin food and third, after a two-day period eating pectin-rich vegetarian food. In order to reduce the short-term influences of the food consumed, investigations II and III were commenced 5 hours after the last meal was eaten. The endogenous serum methanol levels after clearing the bowels reached 0.353 (plus or minus) 0.120 mg/kg, after the consumption of low-pectin food they reached 0.732 (plus or minus) 0.616 mg/kg, and after the consumption of pectin-rich food 1.063 (plus or minus) 0.982 mg/kg. The differences, however, could not be regarded as significant. The rate of methanol production after clearing the bowels was determined at 0.277 (plus or minus) 0.081 mg/kg/h, after low-pectin food was consumed at 0.285 + 0.078 mg/kg/h, and after pectin-rich food was consumed at 0.475 (plus or minus) 0.127 mg/kg/h. The difference after pectin-rich food was consumed was significant on the 5 % level. The endogenous levels and the production rates showed a significant positive rank correlation (p lt 0.05). Methanol resorption from the intestines cannot be explained as the only source of endogenous methanol levels. Apparently, pectin-rich food leads to an increase in the rate of endogenous methanol production. Whether pectin-rich food leads to an increase of the endogenous methanol level could not be clarified for certain.<p />
LA  - de
SN  - 0006-5250
UR  - http://dx.doi.org/
ID  - ref1
ER  -