TY - JOUR PY - 1997// TI - About the influence of the ethanol metabolism (zero-order kinetics or Michaelis-Menten kinetics) on the concentration of ethanol in venous blood JO - Blutalkohol A1 - Zink, M A1 - Troger, Hans Dieter A1 - Zink, P. SP - 413 EP - 426 VL - 34 IS - 6 N2 - Taking into consideration the organ compartments lung, liver, stomach and bowel, kidney, muscle, skin and rest, and the blood vessel compartments arteries, veins, pulmonary arteries and pulmonary veins the following results came up during computer simulation: 1. Venous ethanol concentration is always marginally below values calculated using the Widmark formula. This is due to the fact that venous blood contains a lower ethanol concentrations as it is diluted with hepatic blood of a low ethanol concentration. 2. As for the forensically relevant range of above 0.01 per cent no significant differences between the metabolism of ethanol with zero-order and Michaelis-Menten- kinetics could be detected.

LA - de SN - 0006-5250 UR - http://dx.doi.org/ ID - ref1 ER -