TY  - JOUR
PY  - 1986//
TI  - Beneficial effects of ethanol on experimental burns
JO  - American surgeon
A1  - Tikellis, J. I.
A1  - Spillert, C. R.
A1  - Suval, W.
A1  - Lazaro, E. J.
SP  - 53
EP  - 55
VL  - 52
IS  - 1
N2  - Alcohol has been demonstrated to produce cutaneous vasodilation. The burn wound is characterized by a compromised microcirculation which is amenable to pharmacologic manipulation to improve the final outcome of the injury. Various agents including heparin, aspirin, nonsteroidal anti-inflammatory agents have been employed to maintain a patent microcirculatory bed. Ethanol has been used in the present study in a murine burn model as a vasodilator administered immediately preburn and post-burn. Preburn administration of ethanol significantly improved the mean burn severity at 48 hr compared to ethanol given post-burn. Ethanol, acting as a vasodilator, improves dermal circulation post-burn and reduces the overall extent of injury.<p /> <p>Language: en</p>
LA  - en
SN  - 0003-1348
UR  - http://dx.doi.org/
ID  - ref1
ER  -