TY - JOUR PY - 1986// TI - The behavioral actions of diazepam and oxazepam are similar JO - Psychopharmacology A1 - Mewaldt, S. P. A1 - Ghoneim, M. M. A1 - Hinrichs, J. V. SP - 165 EP - 171 VL - 88 IS - 2 N2 - In a double-blind and randomized study, we assessed the comparative pharmacodynamic profiles and behavioral effects of diazepam and oxazepam administered to young healthy volunteers. Diazepam 0.3 mg/kg or oxazepam 1.2 mg/kg or placebo were each administered orally to 13 subjects who were tested with tasks which measured learning and memory, cognition, psychomotor performance and mood before and for 9 h after treatment. The two drugs had similar actions, although subjective effects were milder after oxazepam, which also had a slower onset of action. There was no evidence of rebound behavioral impairment.
Language: en
LA - en SN - 0033-3158 UR - http://dx.doi.org/ ID - ref1 ER -