TY  - JOUR
PY  - 2014//
TI  - Neuropsychological outcome after carbon monoxide exposure following a storm: a case-control study
JO  - BMC neurology
A1  - Pages, Bérengère
A1  - Planton, Mélanie
A1  - Buys, Sophie
A1  - Lemesle, Béatrice
A1  - Birmes, Philippe
A1  - Barbeau, Emmanuel Joseph
A1  - Maziero, Stéphanie
A1  - Cordier, Laurie
A1  - Cabot, Claudine
A1  - Puel, Michèle
A1  - Genestal, Michèle
A1  - Chollet, François
A1  - Pariente, Jérémie
SP  - 153
EP  - 153
VL  - 14
IS  - 1
N2  - BACKGROUND: The cognitive consequences of carbon monoxide (CO) poisoning are well described. However, most studies have been carried out without an ad-hoc group of control subjects. The main aim of this study was to evaluate cognitive and psychiatric outcome after CO exposure during the storm Klaus in the South West of France (January 2009) in a homogeneous group of patients compared to a group of 1:1 paired controls. <br><br>METHODS: Patients and controls were asked to fill out questionnaires about quality of life and cognitive complaints. They then underwent a cognitive assessment derived from the Carbon Monoxide Neuropsychological Screening Battery. Psychiatric assessment was performed using subtests of the Mini International Neuropsychiatric Interview. <br><br>RESULTS: 38 patients and 38 paired controls were included (mean age 38.8 years) and evaluated 51 days after the poisoning. No difference was found between groups on the cognitive complaint questionnaire but patients had a lower quality of life than controls. Patients showed significantly lower cognitive performance than controls on processing speed, mental flexibility, inhibition and working and verbal episodic memories. Patients were more depressed than controls, and suffered more from post-traumatic stress disorder. <br><br>CONCLUSIONS: We report the first study investigating cognitive and psychiatric outcome in consecutive patients after CO poisoning during a natural disaster, using a group comparison method. CO poisoning during storms needs to be dealt with adequately and clinicians should be aware of its possible consequences.<p />  <p>Language: en</p>
LA  - en
SN  - 1471-2377
UR  - http://dx.doi.org/10.1186/1471-2377-14-153
ID  - ref1
ER  -