TY  - JOUR
PY  - 1987//
TI  - Naltrexone in treatment of self injurious behavior: a clinical study
JO  - Research in developmental disabilities
A1  - Szymanski, L.
A1  - Kedesdy, J.
A1  - Sulkes, S.
A1  - Cutler, A.
A1  - Stevens-Our, P.
SP  - 179
EP  - 190
VL  - 8
IS  - 2
N2  - It has been suggested that the parenteral opiate antagonist, naloxone, might ameliorate self-injurious behavior. However, clinical studies have had conflicting results. We have evaluated whether a potent oral opiate antagonist, naltrexone, is effective in the treatment of this condition. The study was conducted on two young, profoundly mentally retarded adults, who exhibited intractable self-injurious behavior. A double-blind, placebo-controlled, within-subject-withdrawal design was utilized. One subject was studied for 12 weeks and the other one for 18 weeks. No measurable effects on the self-injurious behavior were observed.<p /> <p>Language: en</p>
LA  - en
SN  - 0891-4222
UR  - http://dx.doi.org/
ID  - ref1
ER  -